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Health & Longevity | MAF Official | Japan 🇯🇵 | Japan, Hawaii & Australia | Worldwide Shipping

27/05/2026

Did you notice our updated packaging?

MAF Capsules Triple now comes with a refreshed label and is carefully shipped in its own box — designed to deliver a more refined and premium experience from the moment it arrives.

Featuring patented MAF technology, MAF Capsules Triple is made in Japan and formulated for those who value quality, consistency, and daily self-care. Each bottle contains 60 capsules and includes 3x MAF ingredient content, supporting your wellness routine with a clean, thoughtful approach.

Same trusted MAF Capsules Triple.
A more elevated look.
A more complete experience.

Nurture your future self with Saisei MAF.

21/05/2026

The world isn’t just getting older —
it’s aging faster than ever.

As the global population ages,
conditions such as cardiovascular disease,
cognitive decline, and metabolic disorders
are becoming increasingly common.

But a shift is happening in science.

Instead of treating diseases one by one,
research is beginning to focus on
the biology of aging itself.

What if we could support the systems
that influence multiple conditions at once?

Emerging research is exploring how
cellular maintenance, genomic stability,
and immune resilience
may shape long-term health.

At Saisei Pharma, our work focuses on
understanding these interconnected processes —
and how they influence aging at the cellular level.

Because longevity isn’t just about living longer.
It’s about maintaining function over time.

Save this to rethink the future of health.

20/05/2026

In severe viral infections,
immune balance can be significantly disrupted.

One commonly observed change is lymphopenia —
a reduction in lymphocyte levels,
which are essential for immune defense.

Clinical studies have explored how MAF supplementation
may influence absolute lymphocyte count (ALC)
in hospitalized COVID-19 patients.

Findings indicated:

✔ Support in maintaining lymphocyte levels
✔ Faster recovery of ALC over time

These observations suggest that supporting immune regulation
may help maintain resilience
during periods of immune stress.

Understanding how the immune system responds
under pressure remains a key focus of ongoing research.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to better understand immune health.

19/05/2026

Inflammation is a necessary response —
but balance is everything.

In preclinical studies using mouse models exposed to LPS
(an agent used to simulate immune challenge),
Dietary MAF was observed to influence inflammatory responses.

Findings showed:

✔ Reduced levels of pro-inflammatory cytokines
such as TNF-α and IL-1β
✔ No signs of excessive immune suppression

These results suggest that MAF may help support
a more balanced immune response
during periods of inflammatory stress.

Rather than simply suppressing inflammation,
maintaining immune regulation may be key.

Ongoing research continues to explore
how nutritional immune modulation
may influence inflammation-related outcomes.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to better understand immune balance.

18/05/2026

Aging is not only about time —
it’s also about what accumulates in the body.

Advanced glycation end products (AGEs)
are compounds that build up over time
and are associated with cellular stress
and cognitive decline.

In a 12-month study involving elderly participants in rehabilitation,
Saisei Pharma measured changes in plasma AGE levels.

Findings showed:

✔ The control group experienced a significant increase in AGE accumulation
✔ Participants receiving MAF supplementation maintained more stable AGE levels

These observations suggest that supporting immune and inflammatory balance
may play a role in limiting AGE accumulation.

Understanding how these processes change over time
is key to supporting long-term cognitive and cellular health.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to better understand aging at the cellular level.

15/05/2026

Severe viral infections can place significant stress on the immune system.

In hospitalized COVID-19 patients,
immune dysregulation and reduced lymphocyte levels
have been widely observed.

In a clinical study conducted across Ukraine and Italy,
Saisei Pharma investigated the use of MAF (Macrophage Activating Factor)
alongside standard care.

Findings from the study included:

✔ Increased lymphocyte counts by Day 7
✔ Lower rates of ICU admission and need for ventilation
✔ A statistically significant reduction in mortality
✔ No significant adverse events reported

These observations provide insight into how
targeted immune modulation may influence
responses during acute viral conditions.

Further research is ongoing to better understand
the role of immune balance in complex infections.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to stay informed on immune research.

14/05/2026

Brain development is not only neurological —
it is also deeply connected to the immune system.

Research suggests that immune balance
and inflammation may influence neurodevelopmental processes.

In particular, microglia — the brain’s resident immune cells —
play a role in shaping neural connections
through processes such as synaptic pruning.

When immune regulation is disrupted,
this delicate balance may be affected.

Studies have explored how neuroinflammation
and immune dysregulation may be associated with
neurodevelopmental conditions, including ASD.

At Saisei Pharma, our research investigates
how immune balance and inflammatory pathways
interact with brain health and development.

Understanding the immune–brain connection
remains a key focus in advancing modern health science.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to better understand brain development.

13/05/2026

Could one gene influence how we age?

The Klotho gene is widely studied for its role
in cellular protection, metabolic balance, and aging processes.

Research suggests that higher Klotho expression is associated with:
– Aging resilience
– Cognitive function
– Cardiovascular health

At Saisei Pharma, clinical studies on Dietary MAF have explored:

✔ Increased Klotho gene expression
✔ Potential links between Klotho, telomerase activity, and aging biology
✔ The role of Klotho in cellular protection and longevity research

These findings continue to shape our understanding
of how aging is regulated at the cellular level.

Ongoing research aims to further explore
how Klotho expression may contribute to long-term health and longevity.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to explore the science of longevity.

12/05/2026

Can cellular aging be influenced?

In a recent clinical study, Saisei Pharma explored
the effects of Dietary MAF on telomere length —
a key marker of biological aging.

Over a 6-month period:

✔ Participants showed increases in telomere length compared to baseline
✔ Telomerase-related activity (TERT & TERC) was observed in preclinical research
✔ No significant adverse effects were reported
✔ All participants completed the study protocol

These findings suggest a potential role for MAF
in supporting cellular health and aging resilience.

Ongoing research continues to explore
its relationship with key aging markers,
including Klotho gene expression and telomere maintenance.

As science advances, understanding how cells age
remains at the forefront of longevity research.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to follow the future of aging science.

11/05/2026

Healing starts at the cellular level.

Tissue repair and regeneration depend on
how well the immune system is regulated.

Macrophages play a central role in this process —
supporting wound healing, coordinating immune responses,
and helping maintain tissue balance.

At Saisei Pharma, our research explores how Dietary MAF
may support immune balance and inflammatory regulation,
key factors involved in cellular repair.

Studies suggest that MAF-activated macrophages
may help guide tissue recovery
through a more adaptive response —
not limited to a fixed M1/M2 framework.

Understanding this dynamic immune activity
is essential for supporting long-term cellular health.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to rethink how your body heals.

07/05/2026

Aging isn’t just measured in years.

It’s written in your genes.

DNA methylation is an epigenetic process
that regulates how genes are expressed —
and these patterns change as we age.

Scientists use epigenetic clocks to track these changes,
offering insight into biological age
beyond the number of years you’ve lived.

At Saisei Pharma, our research explores how
these epigenetic markers relate to aging resilience,
and how Dietary MAF may support cellular health
through immune and inflammatory pathways.

Understanding aging at the molecular level
is key to understanding long-term health.

Learn more:
Japan / Europe: https://saisei-pharma.co.jp/en/

Australia / NZ: https://saiseiaustralia.com.au/

USA / Canada: https://saisei-hawaii.com/

Save this to rethink how aging is measured.

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